Southampton vs Middlesbrough Prediction, Betting Tips, Lineups & Odds | 27 Sep 2025

Championship Betting Preview: Southampton vs Middlesbrough

Southampton host Middlesbrough in this Championship game at St. Mary's, with kick-off set for 22:00 on Saturday 27 September. Our betting preview features expert predictions, betting tips, the latest odds, H2H stats, team news and both predicted and confirmed lineups.

We Predict a Close Encounter

Middlesbrough look a nice wager to topple Southampton and we can take them at 1.80 with a +0.25 goal headstart on the Asian Handicap. This means dividing our stake equally between 0 and +0.5 in the hope of a payout.

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Most Recent H2H Clash Ended 1-1

Southampton lost away from home in their last Championship game. Hull City won 3-1 at MKM Stadium. The Saints recorded four shots on target and boasted 71% possession, while Adam Armstrong registered the goal.

Four days ago, Southampton visited Liverpool in the EFL Cup and were defeated 2-1.

Middlesbrough won their previous game, beating West Bromwich Albion at home. It was a 2-1 win at Riverside Stadium. Rob Edwards' team were restricted to 41% possession and recorded four shots on goal, with David Strelec and Kaly Sene on the scoresheet.

Head-to-Head Statistics

When the teams last went head-to-head, we saw Middlesbrough draw 1-1 away to Southampton at St. Mary's.

Championship		G	W	D	L	GF	GA	GD	GD	P
1	Middlesbrough	6	5	1	0	11	4	7	11:4	16
19	Southampton	6	1	3	2	7	9	-2	7:9	6

View Full Table

Southampton have 1 win, 5 losses and 4 draws, averaging 0.8 goals from 3.3 shots on goal and 11.4 attempts. The South Coast side have averaged 53.4% possession and 5.5 corners per game, with their opponents scoring 1.5 goals from 3.7 shots on goal, 14.5 attempts and 5.4 corners.

Top goalscorer Ryan Manning has found the net 2 times, with Adam Armstrong, Cameron Archer, Taylor Harwood-Bellis and Jay Robinson scoring 1 each. Ryan Fraser and Mateus Fernandes have racked up the most assists with 2, while goalkeeper Aaron Ramsdale has one clean sheet.

Middlesbrough have won 6, lost 2 and drawn 2, with an average of 1.4 goals from 11.3 attempts and 5.0 shots on goal. There’s been an average of 53.4% possession, 6.4 corners awarded and 4.1 corners against them, while they’ve conceded 0.9 goals from 10.8 attempts and 3.4 shots on goal.

Tommy Conway and Finn Azaz have top scored with 3, while David Strelec is next on 1. Hayden Hackney has been the chief assist maker in the previous 10 games with 3.

Predicted & Confirmed Lineups

Southampton predicted lineup (4-2-3-1): Gavin Bazunu (GK), Mads Roerslev, Joshua Quarshie, Jack Stephens, Ryan Manning, Flynn Downes, Shea Charles, Adam Armstrong, Finn Azaz, Ryan Fraser, Damion Downs.

Middlesbrough predicted lineup (3-4-2-1): Solomon Brynn (GK), Luke Ayling, Dael Fry, Alfie Jones, Callum Brittain, Aidan Morris, Hayden Hackney, Matthew Targett, Sverre Nypan, Tommy Conway, David Strelec.

Southampton vs Middlesbrough Prediction & Betting Tips

Get set for Southampton vs Middlesbrough with our full betting breakdown, complete with an expert match prediction, a likely final score, top corners play, player prop picks and a value-driven bet builder.

Match Prediction

When Middlesbrough kick off this Championship match, we will wager them at 1.80 on the Asian Handicap +0.25. Avoiding defeat seems well within their capability and a win could be on the cards.

It's essential to know the players who are missing for the next clash along with the form for each of the two sides. If you’re looking for the best Championship stats, we will showcase them and they provide the foundation for our football picks.

Key Southampton vs Middlesbrough league stats:

• The +0.25 line has been covered by Middlesbrough in 6 consecutive games.
• The +0.25 line has been covered by Middlesbrough in 8 of their last 10 games.
• The +0.25 line has been covered by Middlesbrough in 14 of their last 20 games.
• The -0.25 line hasn’t been covered by Southampton in 5 consecutive games.

Boro +0.25 Probability

The betting odds at the top bookies suggest our pick carries a 55.6% chance of winning. After careful examination, our tipsters calculate this probability to be somewhere between 60-65%. This is why we regard this as a value bet.

If you’re in search of a larger price, there are lots of options for those wanting to sell goals. The wager is riskier but will provide a bigger reward should it win.

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Our Match Prediction

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Correct Score Prediction

Southampton 1 - 2 Middlesbrough

A 2-1 win in favor of Middlesbrough is available at odds of 10.00. Take a chance on the correct score and get rewarded for predicting the right scoreline.

Player Prop Picks

Corners Prediction

Southampton To Have Most Corners

Southampton have been awarded the most corners in six consecutive games. Southampton should be capable of winning this Corner Match Bet and the odds of 1.84 look value.

League Games

League Games

Last 10 Total For Against

Last 10 at Home Total For Against

Last 10 Away Total For Against

Southampton

Total

10.90 5.50 5.40

Home

11.10 4.10 7.00

Away

7.80 4.20 3.60

Middlesbrough

Total

10.50 6.40 4.10

Home

9.80 6.30 3.50

Away

9.40 4.50 4.90

Latest Corner Odds

Total Corners

Southampton Corners

Middlesbrough Corners

Most Corners

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Southampton vs Middlesbrough Odds

The odds are updated on a frequent basis. You might therefore find that they are different to the ones listed for the above betting predictions.

Game Could Go Right to the Wire According to the Bookies

Southampton are available at 2.14 to come away with a triumph in this Championship clash, meaning a 47% likelihood of winning according to the published betting odds. If you’re interested in wagering Middlesbrough, you can get 3.25 for the underdog.

There’s sometimes a case for betting on the Draw No Bet market, with Southampton available at 1.55 for those who want insurance on their bet. The same applies to opponents Middlesbrough at 2.30.

The Under 2.5 / Over 2.5 Goals betting market suggests that there’s not much between the two options. If you are expecting both teams to score, there’s the chance to back Yes at 1.66 on the BTTS market.

The best football betting sites definitely give customers lots of choice. When it comes to Championship matches, choose from hundreds of markets until you find the most attractive odds.

Adam Armstrong Shortest Odds for First Goalscorer

There is 3.25 available that Adam Armstrong finds the net, while he is available at 6.00 to register the first goal which makes him favourite.

Past Ten Southampton Home Games Have Seen Six Defeats

Southampton have recorded six defeats, three draws and one victory in the previous 10 home matches, netting an average of 0.70 goals per game and conceding 1.70.

Middlesbrough haven’t lost any of their past three away games. The Teeside outfit have racked up four wins, four defeats and two draws in the last 10 away matches, scoring an average of 1.30 goals per game and conceding 1.00.

Southampton were involved in a 1-1 draw when last meeting Middlesbrough at St. Mary's.

Last 10 League Games		W-D-L	G	GF	GA	O2.5	U2.5	B-Y	B-No
Southampton Home Stats		1-3-6	2.40	0.70	1.70	7	3	6	4
Middlesbrough Away Stats		4-2-4	2.30	1.30	1.00	5	5	4	6

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

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Southampton vs Middlesbrough Lineups & Team News

Know who’s in and who’s out for Southampton vs Middlesbrough before making your bets. We’ll update you with predicted and confirmed Championship lineups plus current injury reports.

Southampton Team Page Middlesbrough Team Page